Serotonergic modulation of cognitive computations

Serotonin is a neuromodulator that implicated in awake-sleep cycle, motor behaviors, reward, motivation, and mood. Recent molecular tools for cell-type-specific activity recording manipulation with fine temporal spatial resolutions are providing unprecedentedly detailed data about serotonergic neuromodulation. These newly gained information show substantial differences the signaling effect of neuromodulation depending on projection targets. To find common denominator this diversity, we conjecture evolution originates from time resource available action, learning, development.